RNA-seq based transcriptomic profiling of human and mouse dorsal root ganglion reveals a potential role for Protease Activated Receptor 3 (PAR3) in pain processing
Theodore Price, Andrew Torck, Pradipta Ray, Shayne Hassler, Justin Hoffman, Josef Vagner, Gregory Dussor and Scott Boitano
The mitochondrial complex one inhibitor R419 potently stimulates AMPK in dorsal root ganglion neurons and reduces incision-evoked pain in vivo
Theodore Price, Galo Mejia, Marina Asiedu, Yasumichi Hitoshi and Gregory Dussor
An essential role for eIF4E phosphorylation in peripherally-mediated pain plasticity
Theodore J. Price, Marina N.K. Asiedu, Jamie K. Moy, Arkady Khoutorsky, Dipti V. Tillu, Ohannes K. Melemedjian, Galo L. Mejia, Ji-Young Kim, Christos Gkogkas, Nahum Sonenberg, Gregory Dussor
Spinal dopaminergic projections control the transition to chronic pain via a D1/D5-mediated mechanism
Ji-Young Kim, Galo L. Mejia, Adia Shy, Marina N.K. Asiedu, Elaine Murad, Patrick W. Mantyh, Gregory Dussor, Theodore J. Price
AMPK-mediated control of P-bodies as a novel mechanism of gene expression control in peripheral sensory neurons
Galo L. Mejia, Ohannes K. Melemedjian, Greggory Dussor, Theodore J. Price
Identifying novel drug targets for Pain using Machine Learning approaches
Andrew Torck, Theodore J. Price
Highly potent agonists reveal Protease Activated Receptor Type 2 (PAR2)-dependent hyperalgesic priming relying on central trkB/aPKC maintenance mechanisms
Theodore J. Price, Dipti V. Tillu, Marina N.K. Asiedu
Resveratrol engages AMPK to attenuate ERK and mTOR signalling in sensory neurons and inhibits incision-induced acute and chronic pain
Dipti V. Tillu, Ohannes K. Melemedjian, Marina N. Asiedu, Travis Hughes, Ning Qu, Milena DeFelice, Gregory Dussor, Theodore J. Price
The effects of spinal NMDA receptor activation on KCC2, EphB2 and n-cadherin and its implications for hyperalgesic priming
Ji-Young Kim, Elaine K. Murad, Galo Mejia, Theodore J. Price
AMPK activation is sufficient to inhibit incision induced chronic pain
Dipti V. Tillu, Marina N.K. Asiedu, Ohannes K. Melemedjian, Gregory Dussor, Theodore J. Price
A769662: A novel voltage-gated sodium channel blocker
Marina N.K. Asiedu, Theodore J. Price, Gregory Dussor